Positions
- Assistant Professor
-
Molecular and Human Genetics
草榴社区入口
Houston, United States
Molecular Oncology
- Member
-
Dan L. Duncan Cancer Center
Houston
Addresses
- Jan and Dan Duncan Neurological Research Institute (Lab)
-
1250 Moursund Street
Houston, TX 77030
United States
Phone: (832) 824-8888
tiemo.klisch@bcm.edu
Education
- PhD from International Max Planck Research School
- 08/2006 - G枚ttingen, Germany
- BSc from Georg-August-University
- 04/2003 - G枚ttingen, Germany
- Fellowship at Ehime University
- 09/2000 - Matsuyama, Japan
- Fellowship at Albert Ludwig University
- 09/1999 - Freiburg, Germany
Professional Statement
Brain tumors are a diverse group of neoplasms arising from different cells of the central nervous system. Although brain tumors account for only 2 percent of all cancers, these neoplasms result in a disproportionate share of cancer morbidity and mortality of 5.8 per 100,000 population (annual age-adjusted mortality rate in the US 2008-2012). My lab focuses on the causes and biological differences of adult meningioma.Meningiomas account for almost 40% of all primary brain tumors with 2.5 times higher occurrence in women and African-Americans compared with men and other ethnicities. The total number of meningioma patients who fail treatment or experience uncontrolled local recurrence represent roughly two-thirds of all meningioma patients. Even benign meningiomas are lethal if located in an inaccessible region. Over the past decade, Dr. Patel鈥檚 and my lab have been first to discover the three true biological groups that give rise to meningioma, with one being exclusively responsible for the most aggressive type of meningioma. Our studies have been independently validated by multiple other laboratories, which has led to close collaborations throughout the world.
We are part of the International Meningioma Database and contribute as editors to BMC Cancer and Frontiers in Neuroscience.
For job opportunities and future collaboration, please do not hesitate to contact us.
Websites
Selected Publications
- Labs of Sahm (DKFZ), Bi (Harvard), Klisch (BCM), Patel (BCM), Magill (Northwestern), Raleigh (UCSF), and others "." Nature Medicine. 2023; Pubmed PMID:
- Khan AB, English CW, Bayley V JC, Brandt VL, Shetty A, Hadley CC, Choudhury A, Lu HC, Harmanci AS, Harmanci AO, Magill ST, Raleigh DR, Klisch TJ, Patel AJ "." Acta Neuropathologica. 2023; Pubmed PMID:
- Khan AB, Patel R, McDonald MF, Goethe E, English C, Gadot R, Shetty A, Nouri SH, Harmanci AO, Harmanci AS, Klisch TJ, Patel AJ "." J Neurooncol. 2023; Pubmed PMID:
- Harmanci AO, Harmanci AS, Klisch TJ, Patel AJ "." BMC genomics. 2022; Pubmed PMID:
- Bayley V JC, Hadley CC, Harmanci AO, Harmanci AS, Klisch TJ, Patel AJ "." Science Advances. 2022; Pubmed PMID:
- Jackson HN, Hadley CC, Khan AB, Gadot R, Bayley JC 5th, Shetty A, Mandel J, Jalali A, Gallagher KK, Sweeney AD, Harmanci AO, Harmanci AS, Klisch TJ, Gopinath SP, Rao G, Yoshor D, Patel AJ "." Neurosurgery.; Pubmed PMID:
- Gadot R, Khan AB, Patel R, Goethe E, Shetty A, Hadley CC, Harmanci AS, Klisch TJ, Yoshor D, Sheth SA, Patel AJ "." Neurosurg. 2021; Pubmed PMID:
- Khan AB, Gadot R, Shetty A, Bayley V JC, Hadley CC, Cardenas MF, Jalali A, Harmanci AS, Harmanci AO, Wheeler DA, Klisch TJ, Patel AJ "." Journal of Neuro-Oncology. 2020; Pubmed PMID:
- Zhang H, Qi L, Du Y, Huang LF, Braun FK, Kogiso M, Zhao Y, Li C, Lindsay H, Zhao S, Injac SG, Baxter PA, Su JM, Stephan C, Keller C, Heck KA, Harmanci A, Harmanci AO, Yang J, Klisch TJ, Li X-N, Patel AJ "." Cancers. 2020; Pubmed PMID:
- Patel AJ, Wan YW, Al-Ouran R, Revelli JP, Cardenas MF, Oneissi M, Xi L, Jalali A, Magnotti JF, Muzny DM, Doddapaneni HV, Sebastian S, Heck KA, Goodman JC, Gopinath SP, Liu Z, Rao G, Plon SE, Yoshor D, Wheeler DA, Zoghbi HY, Klisch TJ "." Proc Natl Acad Sci.. 2019; Pubmed PMID:
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